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Dana-Farber's Targeted Protein Degradation Seminar Series
Join us for a seminar that's focusing on the most recent and exciting advances in targeted protein degradation. This event will feature a lecture by The seminar will be presented by Mikolaj Slabicki (Ebert Lab), Hojong Yoon (Fischer Lab), and Jonas Koeppel (Ebert Lab).

Dec 3, 2020 12:00 PM in Eastern Time (US and Canada)

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Speakers

Mikolaj Slabicki, Hojong Yoon, Jonas Koeppel
@Dana-Farber Cancer Institute
Researchers from the Ebert and Fischer lab teamed up to solve the elusive mechanism of a BCL6 degrader, BI-3802. By employing functional screens, biochemical dissection, and structural characterization, they identified that BI-3802 induces BCL6 polymerization, which triggers proteasomal degradation of BCL6. The seminar will be presented by Mikolaj Slabicki (Ebert Lab), Hojong Yoon (Fischer Lab), and Jonas Koeppel (Ebert Lab).