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Dana-Farber's Targeted Protein Degradation Seminar Series
Join us for a seminar that's focusing on the most recent and exciting advances in targeted protein degradation. This event will feature a lecture by Nicolas Thomä.

Dec 17, 2020 12:00 PM in Eastern Time (US and Canada)

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Nicolas Thomä
Group Leader @Friedrich Miescher Institute in Basel
The Thomä laboratory is interested in chromatin-bound machines and their regulation by the ubiquitin proteasome system. Guided by structural biology, we use a range of genetic, chemical and complex biochemical reconstitution tools to study protein function in genome maintenance and transcription. A particular focus is on dissecting how chromatin and the ubiquitin transferase system interplay. In recent years, the lab worked towards understanding how proteins, such as ubiquitin ligases, can be re-programmed by small molecules, and how this insight can be used to develop novel drugs. Dr Nicolas Thomä is a group leader at the Friedrich Miescher Institute in Basel, Switzerland. He is an elected member of the European Molecular Biology Organization (EMBO) and of Academia Europeana. Dr Thomä is the recipient of the Novartis Leading Scientist Award and holds an ERC Advanced Grant. www.thomalab.org